These natural substances are needed for effective communication to occur as it should between cells that are located within the brain. The brain cells that have an effect on various forms of depression are known as norepinephrine and serotonin. When an individual has a deficiency of norepinephrine, it can have an effect on the moods and problems with fatigue that individuals experience when they are depressed. When people suffer from a deficiency of serotonin, it can have an effect on symptoms like irritability, anxiety, and problems with sleeping. There are also other chemical in the body that can have an effect on this type of condition. Deficiencies of cortisol are produced naturally in the body and can affect things like fear, stress, and anger.
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